Figure 4

RARβ expression in HCC cells positively correlates with the susceptibility to fenretinide. (A)Basal expression profile of twelve nuclear receptor genes in Huh-7, HepG2, and Hep3B cells. (B)Fenretinide induced nuclear receptors RARα, β, and γ mRNA in Huh-7 cells. (C)Fenretinide induced RARβ and Nor1 mRNA in HepG2 cells. (D)Comparison of RARβ mRNA level between Huh-7 and HepG2 cells after fenretinide treatment (relative fold of RARβ level between Huh-7 and HepG2 cells). Data from two independent experiments were presented as mean ± S.E.M.