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Table 1 Distribution of age, gender, cigarette smoking, alcohol consumption and dietary factors among controls and cases with colorectal carcinomas and adenomas

From: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas

 

Controls

Carcinomas

High-risk adenomas

Low-risk adenomas

No. of subjects

400

234

229

762

Gender a

    

Male, No (%)

157 (39.3)

128 (54.7)

151 (65.9)

456 (59.8)

Female, No (%)

243 (60.8)

106 (45.3)

78 (34.1)

306 (40.2)

Age b

    

Mean, years (SD)

54.2 (3.3)

67.3(11.2)

57.3 (3.5)

57.3 (3.8)

Smoking status

    

Never smoked, No (%)

156 (46.7)

67 (38.5)

52 (27.1)

206 (31.5)

Ever smoked, No (%)

178 (53.3)

107 (61.5)

140 (72.9)

448 (68.5)

Number of cigarette yearsc, median (25–75 percentile)

213 (58.8–362.0)

300 (120.0–546.0)

350 (210.3–484.8)

314 (137.0–468.0)

Alcohol consumption

    

Never, No (%)

73 (21.8)

43 (25.3)

45 (22.6)

147 (21.9)

Ever, No (%)

262 (78.2)

127 (74.7)

154 (77.4)

523 (78.1)

Number of alcohol units per monthd, median (25–75 percentile)

6.5 (2.5–16.0)

10.5 (4.0–25.0)

9.0 (5.0–20.1)

9.0 (4.5–19.0)

Dietary intake in g/day, median (25–75 percentile)

    

Red meat consumption

25 (16.5–45.0)

24 (12.0–39.4)

27 (16.5–45.0)

27 (16.5–45.0)

Processed meat consumption e

70 (40.2–112.9)

62 (31.6–95.2)

77 (42.1–120.9)

77 (46.1–113.6)

Total meat consumption f

99 (63.5–154.5)

90 (53.4–134.5)

112 (71.0–163.0)

112 (74.9–154.9)

Raw vegetable consumption

52 (22.8–84.8)

41 (19.2–81.0)

42 (19.9–75.0)

45 (22.9–80.1)

Boiled vegetable consumption g

58 (34.9–94.7)

74 (39.2–108.1)

64 (38.7–100.3)

67 (40.2–108.3)

Fruit and berry consumption h

141 (74.1–224.3)

106 (51.9–190.1)

122 (54.7–200.5)

118 (59.7–199.6)

Total fruit, berry and vegetable consumption

265 (166.4–390.9)

250 (149.7–378.4)

230 (156.2–372.1)

241 (157.6–358.7)

Ratio of total meat to total fruit, berry and vegetable intake i

0.38 (0.19–0.71)

0.40 (0.20–0.63)

0.43 (0.26–0.76)

0.45 (0.27–0.82)

  1. a There are significant differences in the number of males and females between the control group and all the case groups, P < 10-4.
  2. b There are significant differences in age between the control group and all the case groups, P < 10-4.
  3. c There are significant differences in number of cigarette years (smoking dose) between the control group and all of the case groups, P = 0.001, P < 10-4 and P < 10-4, respectively.
  4. d There is significant difference in number of alcohol units per month between the control group and the low-risk adenoma group, P = 0.013.
  5. e There is significant difference in processed meat consumption (g/day) between the control group and the low-risk adenoma group, P = 0.041.
  6. f There is significant difference in total meat consumption (g/day) between the control group and the low-risk adenoma group, P = 0.027.
  7. g There is significant difference in boiled vegetable consumption (g/day) between the control group and the low-risk adenoma group, P = 0.035.
  8. h There are significant differences in fruit and berry consumption (g/day) between the control group and the carcinoma and low-risk adenoma groups, P = 0.019 and P = 0.005, respectively.
  9. i There are significant differences in ratio of total meat to total fruit, berry and vegetable intake between the control group and the high- and low-risk adenoma groups, P = 0.035 and P = 0.003, respectively.
  10. Missing values for cigarette smoking, alcohol consumption and dietary factors gave rise to diminished number of cases and controls.