Imbalance | Occurrence | Comment |
---|---|---|
dim(2q22q31) | SCLC (up to 31.8%) | Profile appears region-specific; however, SCLC cases have very rich imbalance pattern with more frequent changes |
dim(2q33q37) | Cervix (up to 30.1%) | Specific terminal 2q deletions are else only found in low frequency in NSCLC and bladder lesions |
enh(5q21q35) | RCC (up to 32.8%) | Specific regional 5q gains are near exclusive for renal carcinomas, and are here part of whole chromosomal changes (20%) or limited to the region |
dim(10q) | SCLC (up to 41.3%), melanocytic, endometrial | Rare as specific changes above "background" |
enh(13q) | CRC (up to 38.6%), gastric | 13q gains are rare except in CRC, esp. compared to the frequent losses in the region |