|
dim(2q22q31)
|
SCLC (up to 31.8%)
|
Profile appears region-specific; however, SCLC cases have very rich imbalance pattern with more frequent changes
|
|
dim(2q33q37)
|
Cervix (up to 30.1%)
|
Specific terminal 2q deletions are else only found in low frequency in NSCLC and bladder lesions
|
|
enh(5q21q35)
|
RCC (up to 32.8%)
|
Specific regional 5q gains are near exclusive for renal carcinomas, and are here part of whole chromosomal changes (20%) or limited to the region
|
|
dim(10q)
|
SCLC (up to 41.3%), melanocytic, endometrial
|
Rare as specific changes above "background"
|
|
enh(13q)
|
CRC (up to 38.6%), gastric
|
13q gains are rare except in CRC, esp. compared to the frequent losses in the region
|
