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Table 2 Immunohistological phenotyping of xenografted CUPs and corresponding clinical specimens

From: Biological characterization of two xenografts derived from human CUPs (carcinomas of unknown primary)

  Capi1 clinical specimen Capi1 xenograft Capi3 clinical specimen Capi3 xenograft
EMA 90% ++ 100% +++ 100% +++ 90% +++
CEA 100% +++ 100% +++ 100% +++ 100% +++
CK7 100% +++ 100% ++ 100% ++ 100% ++
CK20 negative negative 30% + negative
TTF1 negative negative negative 10% ++
EGF-R 90% ++ negative negative negative
c-kit negative negative 70% + 50% +++
  1. Values correspond to the percentage of positive cells and the staining intensity.
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