Table 1 Bortezomib and celecoxib cohort dosing schedules
From: Bortezomib in combination with celecoxib in patients with advanced solid tumors: a phase I trial
Cohorts | Bortezomib (mg/m2) | Bortezomib days of administration | Celecoxib (mg PO bid) |
|---|---|---|---|
Level 1 | 1.0 | 1, 8, 15, 22, 29 q42 days | 200 |
Level 2 | 1.0 | 1, 4, 8, 11 q21 days | 200 |
Level 3 | 1.3 | 1, 8, 15, 22, 29 q42 days | 300 |
Level 4 | 1.3 | 1, 4, 8, 11 q21 days | 300 |
Level 5 | 1.6 | 1, 8, 15, 22, 29 q42 days | 400 |
Level 6 | 1.3 | 1, 4, 8, 11 q21 days | 400 |