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Figure 3 | BMC Cancer

Figure 3

From: Inhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK 4 and inactivation of MMP-2

Figure 3

Cell proliferation and invasion capability decreased after antisense PCDGF construct transfection in SW626 and A2780 cells. A, cell proliferation capability was determined by MTT assay after transfection of antisense PCDGF construct and three control group. Intensity on 540 nm reflects the cell proliferation capability. Values represent the mean ± SE from three independent experiments. B, cell invasion capability was detected by transwell chambers. The ratio of the number of cells migrating through matrigel to the number of cells migrating without matrigel was defined as invasion index. Values represent the mean ± SE from three independent experiments. Intensity on 570 nm of cells and invasion index were looked as criterions judging the capability of proliferation and invasion.

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