Figure 3
From: Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies
MSP analysis of DNA methylation status of the 14-3-3σ gene. Bisulfite-treated genomic DNA was subjected to MSP and amplified products were separated on 1.5% agarose gel. Representative results are shown. The 14-3-3σ mRNA expression levels determined by real-time RT-PCR are shown below. M and U denotes methylated and unmethylated alleles, respectively. PCL denotes plasma cell leukemia; MM, multiple myeloma; CML-CP, chronic phase of chronic myeloid leukemia; PLL, prolymphocytic leukemia.