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Table 2 Classic risk factors of HCC: Alcohol consumption and HBV/HBC

From: UDP-glucuronosyltransferase UGT1A7 genetic polymorphisms in hepatocellular carcinoma: a differential impact according to seropositivity of HBV or HCV markers?

  Controls (N = 142) Cirrhosis (N = 134) HCC (N = 165) HCC vs Controls HCC vs Cirrhosis
  N % N % N % ORa 95%CI ORb 95%CI
Drinks/day c           
0–3 58 44,3% 17 14,0% 23 17,2% 1.0 Ref 1.0 Ref
3–7 38 29,0% 23 19,0% 26 19,4% 1.8 0.9–3.7 1.4 0.5–4.1
7–11 21 16,0% 25 20,7% 40 29,9% 4.9 2.4–10.2 2.7 0.9–7.5
≥ 11 14 10,7% 56 46,3% 45 33,6% 9.5 4.2–21.1 1.5 0.6–4.0
  131c 100,0% 121c 100,0% 134c 100,0%     
m ± sd 5.2d ± 5.2   11.2d ± 8.1   9.7d ± 9.4   3.7f 2.1–6.4 1.07f 0.97–1.5
m ± sd 3.3e ± 3.4   6.7e ± 8.3   5.1e ± 7.1      
Cirrhosis characteristic           
Heavy drinkers-virus(-)    106 84,1% 102 71,8%    1.0 Ref
Virus(+)    20 15,9% 40 28,2%    3.1 1.5–6.3
  1. a: adjusted for age and hospital b: adjusted for age, hospital, time since cirrhosis diagnosis, origin of the cirrhosis (viral(+) or not), and social class c: alcohol variable missing for 50 subjects because the food frequency questionnaire was not available at the beginning of the study d: Lifetime mean consumption e: Consumption at the time of the interview. f: OR per unit of 10 drinks/day