Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells

Figure 4

Rapamycin and 5-Fu synergistically inhibit proliferation of SMMC-7721 cells. SMMC-7721 cells were cultured in the presence of rapamycin (10 nM), or 5-Fu (62.5 μg/ml), or both drugs (10 nM rapamycin 1 h piror to 5-Fu) for 36 h. Cells counts were performed with a hemocytometer. The cell numbers were normalized to the untreated control. The results are shown as the mean ± SD of triplicate samples and are representative of two independent experiments. Statistical significance shown as * and ** was determined by t test, with p > 0.05 defined as significant.

Back to article page