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Table 3 Percentage of the cell death was quantified measuring PI-uptake by flow cytometry. PBTD-1 10 μM.

From: PYRROLO[1,2-b][1,2,5]BENZOTHIADIAZEPINES (PBTDs) induce apoptosis in K562 cells

Time hours

K562 % apop.

IM-Resistant K562 % apop

U937 % apop.

HL60 % apop

Jurkatt % apop

8

34

32

38

39

39

16

60

59

65

66

67

24

64

63

66

68

69