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Table 4 Age and gender adjusted Odds Ratios (95% CI) of gastric cancer for selected gene-gene interaction analyses

From: Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population

   GSTT1 SULT1A1
   Present Null Arg/Arg His car.
NAT2 Fast 1* 1. 38 (0.63–3.01) 1* 1.45 (0. 71–2.95)
  cases/controls 30/93 13/29 23/74 20/48
  Slow 1.07 (0.61–1.88) 3.00 (1.52–5.93) 1.40 (0. 75–2.60) 2.00 (1.03–3.89)
  cases/controls 36/103 26/28 35/81 29/50
   p for interaction† = 0.17 p for interaction = 0.97
   AP‡ = 52% AP = 8%
SULT1A1 Arg/Arg 1* 1.53 (0.86–2.71) - -
  cases/controls 35/122 22/34   
  His carriers 2.30 (1.18–4.45) 2.87 (1.36–6.05) - -
  cases/controls 31/75 17/23   
   p for interaction = 0.70   
   AP = 1%   
  1. * Reference category; † By likelihood ratio test; ‡ Attributable Proportion due to biological interaction (see methods)