Table 2 Odds Ratios (95% CI) of gastric cancer for SNPs in metabolic genes and their frequency distribution among 107 cases and 254 controls
|  |  | Cases % (n) | Controls % (n) | OR (95% CI) * †|
|---|---|---|---|---|
GSTM1 null |  | 56.2 (59) | 52.7 (135) | 1.13 (0.71–1.79) |
GSTT1 null |  | 37.1 (39) | 22.4 (57) | 2.10 (1.27–3.44) |
CYP1A1*2A |  | 20.5 (22) | 22.0 (56) | 0.88 (0.50–1.54) |
CYP2E1*5 |  | 4.7 (5) | 7.8 (20) | 0.54 (0.20–1.50) |
CYP2E1*5A or *6 |  | 14.5 (15) | 10.6 (27) | 1.33 (0.67–2.65) |
NAT2 Slow ‡ |  | 59.8 (64) | 51.8 (131) | 1. 38 (0.88–2.19) |
SULT1A1 | Arg/His | 36.5 (39) | 33.5 (85) | 1.35 (0.82–2.21) |
|  | His/His | 10.3 (11) | 5.1 (13) | 2.46 (1.03–5.90) |
EPHX1 exon 3 | Tyr/His | 38.7 (41) | 36.0 (90) | 1.24 (0.76–2.04) |
|  | His/His | 14.1 (15) | 11.2 (28) | 1.37 (0.67–2.80) |
EPHX4 exon 4 | His/Arg | 30.5 (32) | 37.4 (95) | 0.77 (0.47–1.27) |
|  | Arg/Arg | 5.7 (6) | 2.4 (6) | 2.28 (0.70–7.20) |
Imputed mEH phenotypes ^ | Rapid | 15.8 (15) | 23.7 (59) | 0.60 (0.30–1.15) |
|  | Slow | 25.3 (24) | 21.2 (54) | 1.00 (0.55–1.78) |
|  | Very slow | 8.4 (8) | 8.6 (21) | 0.82 (0.33–2.00) |