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Figure 2 | BMC Cancer

Figure 2

From: S100A7 (Psoriasin), highly expressed in Ductal Carcinoma In Situ(DCIS), is regulated by IFN-gamma in mammary epithelial cells

Figure 2

Psoriasin mRNA levels are downregulated in response to IFN-gamma. Cells were treated 48 hours with 350–1000 u of IFN-gamma and total RNA was prepared. Using real-time polymerase chain reaction (RT-PCR), mRNA level of psoriasin was downregulated in response to IFN-gamma in MCF10A cells (A) and in MDA-MB-468 cells (B). Expression data for psoriasin are presented as ratios, in which the expression data are normalized to an endogenous control (β-actin). Values obtained in control cells were designed as 1 and values obtained from IFN-gamma treated cells were normalized to this from the same run. The data are presented as the mean of three different runs.

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