Skip to main content

Table 5 EGFR haplotype frequencies in the cases and controls, and their association with lung cancer risk

From: Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study

Haplotype†

Controls (n = 1164)

Cases (n = 1164)

 

no. (%)

no. (%)

Adjusted§ OR (95% CI)

P

CGGCT

91 (7.8)

118 (10.1)

1.50 (1.09–2.07)

0.012*

CGGCC

124 (10.7)

110 (9.5)

1.08 (0.80–1.47)

0.60

CGGTT

350 (30.1)

305 (26.2)

1.00

 

TAGCC

227 (19.5)

234 (20.1)

1.24 (0.97–1.58)

0.09

Others‡

372 (32.0)

397 (34.1)

1.24 (0.98–1.54)

0.07

Global P

 

0.08

  
  1. † The order of polymorphisms is as follows: 117378C>T, 142285G>A, 162093G>A, 181946C>T and 187114T>C.
  2. ‡ Twenty-five haplotypes that had a frequency of less than 5%.
  3. § Adjusted for age, gender and pack-years of smoking.
  4. * Bonferroni corrected P-value = 0.048.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us