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Table 2 Statistical analysis of LASP-1 distribution and expression in correlation to clinicopathological and biological parameters. LASP-1 (L) protein expression was analyzed in 83 breast cancer samples. Associations with clinicopathological and biological parameters were analyzed using Mann-Whitney-test (M) and Fisher's exact test (F); n.s.: not significant.

From: Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma

   Total (n = 83) L + (n = 46) L - (n = 37) p-value (Test)
   n % n % n %  
Nodal status N+ 50 60.2 34 73.9 16 43.2 0.0066 (F)
  N- 33 39.9 12 26.1 21 56.8 **
Tumor size T1 39 47 16 34.8 23 62.2 0.0159 (F)
  >T1 44 53 30 65.2 14 37.8 *
Grading G1 3 3.6 0 0 3 8.1 0.9593 (M)
  G2 39 47 24 52.2 15 40.5 n.s.
  G3 41 49.4 22 47.8 19 51.4  
c-erB-2 Her+ 18 21.7 12 26.1 6 16.2 0.3005 (F)
  Her- 65 78.3 34 73.9 31 83.8 n.s.
Estrogen receptor ER+ 60 72.3 33 71.7 27 73 1.0 (F)
  ER- 23 27.7 13 28.3 10 27 n.s.
Progesterone receptor PR+ 51 61.5 26 56.5 25 67.6 0.3673 (F)
  PR- 32 38.5 20 43.5 12 32.4 n.s.
Nuclear positivity NUC+ 24 29 20 43.5 4 11 0.0014 (F)
  NUC- 59 71 26 56.5 33 89 **