Table 2 Statistical analysis of LASP-1 distribution and expression in correlation to clinicopathological and biological parameters. LASP-1 (L) protein expression was analyzed in 83 breast cancer samples. Associations with clinicopathological and biological parameters were analyzed using Mann-Whitney-test (M) and Fisher's exact test (F); n.s.: not significant.

Nodal status

N+

50

60.2

34

73.9

16

43.2

0.0066 (F)

N-

33

39.9

12

26.1

21

56.8

**

Tumor size

T1

39

47

16

34.8

23

62.2

0.0159 (F)

>T1

44

53

30

65.2

14

37.8

*

Grading

G1

3

3.6

0

0

3

8.1

0.9593 (M)

G2

39

47

24

52.2

15

40.5

n.s.

G3

41

49.4

22

47.8

19

51.4

c-erB-2

Her+

18

21.7

12

26.1

6

16.2

0.3005 (F)

Her-

65

78.3

34

73.9

31

83.8

n.s.

Estrogen receptor

ER+

60

72.3

33

71.7

27

73

1.0 (F)

ER-

23

27.7

13

28.3

10

27

n.s.

Progesterone receptor

PR+

51

61.5

26

56.5

25

67.6

0.3673 (F)

PR-

32

38.5

20

43.5

12

32.4

n.s.

Nuclear positivity

NUC+

24

29

20

43.5

4

11

0.0014 (F)

NUC-

59

71

26

56.5

33

89

**