Figure 4

Cellular LASP-1 expression pattern visualized by confocal microscopy. Non-confocal (A+B) and confocal (C-E) microscopy of LASP-1 immunostaining in BT-20 breast cancer cells revealed that LASP-1 (red) is mainly detectable in focal contacts (A) and in the cytosol (C). In addition, more than 30% of the cells show a nuclear staining (B+E), and in some cells a perinuclear localization of LASP-1 is visible (B+D).