Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population

BMC Cancer

Table 1 Distribution of characteristics of study subjects

Characteristic		Cases (N = 434)	Controls (N = 512)	p-value^a
Gender, N (%)	Male	322(74.19)	373(72.85)
	Female	112(25.81)	139(27.15)	0.6415
Age, N(%)	< 30 years	102(23.50)	122(23.83)
	30–39 years	167(38.48)	186(36.33%)
	40–49 years	115(26.50)	131(25.59%)
	> = 50 years	50(11.52)	73(14.26%)	0.6302
VCA_IgA(%)^b	0 (< 1:10)	28 (6.85)	404(81.65)
	1 (1:10–1:20)	32(7.82)	70(14.14)
	2 (1:40)	31 (7.58)	16 (3.23)	< 0.0001
	3 (> = 1:80)	318 (77.75)	5 (1.01 %)
	No data	25	17

Note: ^a P-values obtained from chi-square tests. ^b Subjects were divided into 4 titer categories: 0, Subjects with VCA-IgA antibody titers less than 1: 10; 1, Subjects with VCA-IgA antibody titers equal to 1: 10 or 1: 20; 2, Subjects with VCA-IgA antibody titers equal to 1: 40; 3, Subjects with VCA-IgA antibody titers more than 1:80. Not all the cases and controls have EBV VCA antibody titers available.

ISSN: 1471-2407