Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma

BMC Cancer

Table 4 Mean values of normalised levels of NDRG2 mRNA in adenomas¹.

	mRNA level in normal tissue Mean (SD)	p^a	mRNA level in adenomas Mean (SD)	p^a	p^b
Mild/moderate Dysplasia	0.042 (0.012)	NS	0.032 (0.014)	NS	< 0.001
Severe Dysplasia	0.040 (0.014)	NS	0.034 (0.011)	NS	NS

NS = not significant.
¹Cases of adenomas were divided into mild/moderate (n = 52) or severe (n = 20) according to the diagnosed degree of dysplasia.
^a p value when expression levels were compared to the control group of healthy individuals using one-way ANOVA with a Tukey's post test.
^b p value for comparison of mRNA expression levels in normal and tumor samples from the same individual using a paired two-tailed T-test.

ISSN: 1471-2407