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Table 3 Mean values of normalised levels of NDRG2 mRNA in normal and affected colonic tissues.

From: Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma

  mRNA level in normal tissue Mean (SD) pa mRNA level in adenomas/carcinomas Mean (SD) pa pb
Control 0.034 (0.009)     
Low-risk Adenoma 0.044 (0.014) NS 0.0407 (0.017) NS NS
High-risk Adenoma 0.041 (0.012) NS 0.0307 (0.011) NS < 0.001
Carcinoma Normal (distant) 0.027 (0.015) NS 0.0136 (0.012) < 0.001 < 0.001 c
Carcinoma Normal (adjacent) 0.034 (0.021) NS    < 0.001 d
  1. NS = not significant.
  2. a p value when expression levels were compared to the control group of healthy individuals using one-way ANOVA with a Tukey's post test.
  3. b p value for comparison of mRNA expression levels in normal and tumor samples from the same individual using a paired two-tailed T-test.
  4. c p value when normal (distant) and corresponding tumor sample were compared.
  5. d p value when normal (adjacent) and corresponding tumor sample were compared.