Figure 2
From: Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
NDRG2 mRNA levels decrease with increasing Dukes' stage. Samples with colorectal cancer (CRC) staged after the Dukes' staging system with 13 samples categorised as Dukes' A, 19 samples as Dukes' B and 18 samples as Dukes' C. The graph shows the normalised level of NDRG2 mRNA in samples from the different Dukes' stages. Calculating linear regression using each column of data resulted in a statistically significant linear trend (p < 0.05) for a decrease in NDRG2 level with increasing Dukes' stage.