Figure 4
From: Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells
NBT-272 treatment of human MB cells results in reduced c-MYC binding activity. NBT-272 treatment (24 h) of MB cells resulted in a reduction of c-MYC binding activity as determined by the ELISA-based TransAM-c-MYC activity assay. Data show the mean absorbance ± SD (n = 3; ± SD). *Significantly different from controls (solvent only treated cells), determined by one-way ANOVA (**:P < 0.005, *:P < 0.05).