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Table 1 The effect of doranidazole on human colorectal cell lines 3 days after irradiation under hypoxia

From: The radiosensitizing effect of doranidazole on human colorectal cancer cells exposed to high doses of irradiation

Irradiation

Dead Cells (%)

 

VoLo

HT-29

DLD-1

Colo 201

SW 620

30 Gy irradiation

15.7 ± 1.6

21.9 ± 3.7

16.7 ± 1.9

12.7 ± 2.4

19.5 ± 0.9

30 Gy irradiation + Doranidazole (5 mM)

22.2 ± 2.9 *

33.8 ± 4.0 *

28.9 ± 3.5 *

31.4 ± 1.9 *

27.0 ± 1.9 *

  1. * P < 0.01, compared with 30 Gy irradiation