The 2G allele of promoter region of Matrix metalloproteinase-1 as an essential pre-condition for the early onset of oral squamous cell carcinoma

Table 5 Multivariate analysis of factors affecting OSCC

A Results of factors affecting OSCC
	βcoefficient	OR	95% CI of OR	p
2G+	0.83	2.30	(1.15–4.58)	0.0180
Age	0.90	2.47	(1.47–4.14)	0.0006
B Results showing the alleles independently associated with OSCC (adjusted for age and gender).
Allele	β coefficient	OR	95% CI of OR	p
1G/2G	0.782	2.187	(1.06–4.51)	0.034
2G/2G	0.907	2.476	(1.20–5.13)	0.015

A: 2G+ : 2G- = 0, 2G+ = 1
Age : <45 = 0, ≧45 = 1
B: With adjustment for age and gender Alleles are included as multinomial variables with categorical coding in reference to 1G/1G allele.
% concordance = 74.9%.
Hosmer-Lemeshow Goodness-of-fit test: χ² test = 0.996 ; p = 0.998

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