An integrated analysis of genes and pathways exhibiting metabolic differences between estrogen receptor positive breast cancer cells

Table 2 Gene distribution in the individual GO terms

	MCF-7	No. of Genes	%	ZR75-1	No. of Genes	%
Process (BP)	Physiological Process	238	65.0	Cellular Process	214	58.5
	Cellular Process	232	63.4	Physiological Process	210	57.4
	Cellular Physiological Process	217	59.3	Cellular Physiological Process	202	55.2
	Metabolism	179	48.9	Metabolism	156	42.6
Function (MF)	Catalytic Activity	109	29.8	Catalytic Activity	93	25.4
	Protein Binding	55	15.0	Protein Binding	47	12.8
	Hydrolase Activity	48	13.1	Transporter Activity	40	10.9
	Transporter Activity	39	10.7	Hydrolase Activity	29	7.9
Component (CC)	Cell	229	62.6	Cell	212	57.9
	Intracellular	199	54.4	Intracellular	173	47.3
	Organelle	174	47.5	Organelle	155	42.3
	Membrane-bound Organelle	143	39.1	Membrane-bound Organelle	131	35.8

The distribution of genes within the individual GO terms was higher in MCF-7 cells compared to ZR75-1, though the pattern of gene distribution was similar. % denotes percentage of coverage.

ISSN: 1471-2407