Table 7 Most common and serious Adverse events During TMZ/WBRT treatment according to Common Toxicity Criteria extended by National Cancer Institute, (NCI CTC) in the 59 enrolled patients.
| Â | Grade 2 | Â | Grade 3 | Â | Grade 4 | Â |
|---|---|---|---|---|---|---|
Toxicity | No. pts | % | No. pts | % | No. pts | % |
Neutropenia | 15 | 25 | 9 | 15 | - | - |
Thrombocytopenia | 4 | 7 | 2 | 3 | 1 | 1 |
Anemia | 7 | 12 | 8 | 13 | - | - |
Alopecia | 2 | 3 | - | - | - | - |
Vomiting | 6 | 10 | 2 | 3 | Â | Â |
hand and foot syndrome | 2 | 3 | - | - | - | - |
Headache | 5 | 8 | 1 | 1 | - | - |
Nausea | 5 | 8 | 2 | 3 | - | - |
Tremor | 4 | 7 | 2 | 3 | - | - |
Nerosensory | 3 | 5 | - | - | - | - |
Fatigue | 7 | 12 | 2 | 3 | - | - |
Rash | 8 | 13 | 3 | 5 | - | - |