From: TGFB1 and TGFBR1 polymorphisms and breast cancer risk in the Nurses' Health Study
Genotype | Cases (%) | Controls (%) | OR (95% CI)* |
---|---|---|---|
L10L (T/T) | 277 (41.3) | 613 (37.1) | 1.00 (Ref.) |
L10P (T/C) | 305 (45.5) | 797 (48.3) | 0.81 (0.66 – 0.99) |
P10P (C/C) | 89 (13.3) | 241 (14.6) | 0.79 (0.59 – 1.06) |
 |  |  | p-trend = 0.04 |
-509 C/C | 354 (52.4) | 786 (47.3) | 1.00 (Ref.) |
-509 C/T | 276 (40.8) | 723 (43.5) | 0.82 (0.67 – 1.00) |
-509 T/T | 46 (6.8) | 154 (9.3) | 0.63 (0.43 – 0.92) |
 |  |  | p-trend = 0.005 |