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Table 3 Analysis of 14-3-3 zeta protein expression in OSCCs: Correlation with clinicopathological parameters

From: Over-expression of 14-3-3zeta is an early event in oral cancer

Clinicopathological Features

Total Cases

14-3-3 zeta overall Positivity

14-3-3 zeta Cytoplasmic Positivity

14-3-3 zeta Cytoplasmic & Membrane Positivity

14-3-3 zeta Cytoplasmic & Nuclear Positivity

 

N

n

(%)

n

(%)

n

(%)

n

(%)

OSCC

120

95

(79)

77

(65)

8

(6)

10

(8)

Differentiation

         

WDSCC

67

51

(76)

43

(64)

4

(6)

4

(6)

MDSCC

47

39

(83)

29

(61)

4

(8)

6

(12)

PDSCC

6

5

(83)

5

(83)

0

 

0

 

Tumor Stage

         

T1

20

17

(85)

15

(75)

1

(5)

1

(5)

T2

36

24

(66)

18

(50)

2

(5)

4

(11)

T3

32

27

(84)

19

(60)

5

(15)

3

(9)

T4

32

27

(84)

25

(78)

0

 

2

(6)

Nodal Status

         

N-

66

51

(77)

43

(65)

4

(6)

4

(6)

N+

54

44

(81)

34

(63)

4

(7)

6

(11)

Habits

         

Non consumer

16

12

(75)

10

(62)

1

(6)

1

(6)

Tobacco consumer

104

83

(80)

67

(64)

7

(7)

9

(9)

  1. # OSCCs: Age Range: 29–75 yrs, Median age, 53 yrs; No. of Males: 95; Females:25 ; Non consumers :16; Tobacco consumers (including betel quid usage):104 (p > 0.05) No correlation was observed between 14-3-3ζ protein expression and histopathological grading, tumor stage and nodal status of OSCCs.