Table 2 Analysis of 14-3-3ζ protein expression in Oral Pre-Malignant lesions: Correlation with clinicopathological parameters
From: Over-expression of 14-3-3zeta is an early event in oral cancer
Clinicopathological Features | Total Cases | 14-3-3 zeta overall Positivity | 14-3-3 zeta Cytoplasmic Positivity | 14-3-3 zeta Cytoplasmic & Membrane Positivity | 14-3-3 zeta Cytoplasmic & Nuclear Positivity | ||||
|---|---|---|---|---|---|---|---|---|---|
| Â | N | n | (%) | n | (%) | n | (%) | n | (%) |
Normal | 66 | 25 | (38) | 25 | (38) | 0 | Â | 0 | Â |
OPLs | 89 | 61 | (69) | 46 | (52) | 8 | (9) | 7 | (8) |
Differentiation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Hyperplasiaa | 48 | 33 | (68) | 25 | (52) | 4 | (8) | 4 | (8) |
Dysplasia | 41 | 28 | (67) | 21 | (51) | 4 | (10) | 3 | (7) |
   Mild Dysplasiab | 19 | 10 | (53) | 9 | (47) | 1 | (5) | 0 |  |
   Moderate Dysplasia | 14 | 11 | (78) | 8 | (57) | 2 | (14) | 1 | (7) |
   Severe Dysplasia | 8 | 7 | (87) | 4 | (50) | 1 | (12) | 2 | (25) |
Habits | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Non consumer | 12 | 7 | (58) | 5 | (42) | 1 | (8) | 1 | (8) |
   Tobacco consumer | 77 | 54 | (70) | 41 | (53) | 7 | (9) | 6 | (8) |