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Table 5 Summary of HRM and sequencing results for the breast tumour panel

From: High resolution melting for mutation scanning of TP53exons 5–8

Sample ID HRM results Sequencing results
  Exon 5 5a Exon 5 5b Exon 6 Exon 7 Exon 8 Nomenclature Protein change Exon
B1 wt wt wt wt wt NA NA NA
B2 wt wt wt wt wt NA NA NA
B3 wt MUT wt wt wt 524G>A R175H 5
B4 wt wt wt MUT wt 711G>A M237I 7
B5 wt wt wt wt wt NA NA NA
B6 wt MUT wt wt wt 527G>T C176F 5
B7 wt wt wt wt wt NA NA NA
B8 wt wt wt wt wt NA NA NA
B9 wt wt wt MUT wt 711G>A M237I 7
B10 wt wt wt wt wt NA NA NA
B11 wt wt wt wt wt NA NA NA
B12 wt wt wt wt wt NA NA NA
B13 wt wt wt wt wt NA NA NA
B14 wt ? wt wt wt 531_533delC frame shift, H178fs 5
B15 wt wt wt wt wt NA NA NA
B16 wt wt MUT wt wt 614A>T Y205F 6
B17 wt wt wt wt wt NA NA NA
B18 wt wt wt wt wt NA NA NA
B19 wt MUT wt wt wt 513_515delGinsAT frame shift, V172fs 5
B20 wt wt wt wt wt NA NA NA
  1. wt - wild-type, MUT – Mutant, het – heterozygous, hom – homozygous, ? – unable to score, NA – not applicable