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Table 3 Series of patients with recurrent gliomas treated with hypofractionated stereotactic radiotherapy (H-FSRT).

From: Radiotherapeutic alternatives for previously irradiated recurrent gliomas

Author Pt. Number Histology Tumor size (ml; median) Median Dose (Gy) Median Fraction Size (Gy) Median survival (months) Rate of Severe Toxiticy/Reoperation rate (%)
Ernst-Stecken et al., 2006 15 GBM 22.4 35 7 - 0%
Hudes et al., 1999 19 (1) GBM (AA) 12.6 30 3 10.5 0%
Laing et al., 1993 22 GBM - 30–50 (range) 5–6 (range) - -
Selch et al., 2000 15 (3;3) GBM (AA/LGG) 12 25 4–6 (range) 6.7 0%
Shepherd et al., 1997 29 (7) GBM/AA (LGG) 24 20–50 (range) 5 11 (GBM/AA) 36%
Vordermark et al., 2005 10 (19) II or III 15 30 5 13.5 26%
Vordermark et al., 2005 9 (19) IV 15 30 5 7.4