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Table 1 Invasive tumors: patient and tumor characteristics by histological type

From: Prognostic value of histopathology and trends in cervical cancer: a SEER population study

Characteristic Non-missing data Microinvasive SCC Carcinoma not otherwise specified Squamous Cell (SCC) Adenoca. excl. mucinous Adeno-squamous Mucinous adeno-carcinoma Small cell carcinoma
   n = 2910 n = 1688 n = 20755 n = 4015 n = 1120 n = 305 n = 196
Age (1) 30989 38 (31~48) 42 (32~58) 50 (39~64) 47 (37~62) 44 (36~57) 50 (41~66) 48 (35~63)
Marital status (married)(2) 27999 1451 (55%) 736 (52%) 9193 (49%) 2102 (58%) 548 (53%) 160 (57%) 95 (51%)
Race 30764        
   White non-hisp (2)   2041 (71%) 1191 (72%) 13797 (67%) 3066 (77%) 785 (70%) 229 (75%) 127 (65%)
   White hispanic (2)   199 (7%) 96 (6%) 1671 (8%) 236 (6%) 75 (7%) 19 (6%) 14 (7%)
   Black (2)   362 (13%) 278 (17%) 3430 (17%) 318 (8%) 157 (14%) 23 (8%) 21 (11%)
   Other (2)   279 (10%) 95 (6%) 1735 (8%) 357 (9%) 97 (9%) 34 (11%) 32 (16%)
Tumor size (mm) (1)(3) 6352 1 (1~2) 2 (1~53) 40 (17~60) 25 (10~45) 30 (20~50) 29 (20~47) 45 (29~69)
High histological grade (2) 16378 95 (28%) 248 (86%) 5722 (49%) 821 (28%) 485 (70%) 61 (26%) 142 (100%)
Number of nodes removed (1)(4) 14178 0 (0-0) 0 (0-0) 0 (0–9) 0 (0–17) 1 (0–18) 5 (0–21) 0 (0–11)
Node-positive status (2) 5243 1 (0%) 9 (18%) 679 (21%) 143 (12%) 92 (24%) 33 (29%) 21 (48%)
Log odds nodal involvement (1)(5) 4497 -3.4 (-3.9~-2.9) -3.1 (-3.7~-1.9) -3.4 (-3.9~-2.5) -3.6 (-3.9~-2.9) -3.3 (-3.8~-2.3) -3.4 (-3.9~-1.9) -2.7 (-3.7~-1.2)
AJCC Stage (6)         
   I (2) 8831 1583 (99%) 373 (70%) 4674 (51%) 1657 (71%) 407 (60%) 100 (54%) 37 (32%)
   II (2) 2104 11 (1%) 51 (10%) 1708 (19%) 226 (10%) 74 (11%) 18 (10%) 16 (14%)
   III (2) 2223 7 (0%) 50 (9%) 1771 (20%) 216 (9%) 115 (17%) 35 (19%) 29 (25%)
   IV (2) 1358 4 (0%) 61 (11%) 925 (10%) 226 (10%) 77 (11%) 31 (17%) 34 (29%)
Hysterectomy (2) 17994 1553 (72%) 364 (46%) 5302 (48%) 1966 (68%) 540 (67%) 146 (69%) 63 (47%)
Radiotherapy (2) 30747 128 (4%) 435 (26%) 13084 (64%) 1819 (46%) 643 (58%) 183 (60%) 120 (62%)
  1. (1) Values are: median (lower ~ upper quartiles).
  2. (2) Values are: number of patients (%). Rounded percentages are computed excluding cases with missing data.
  3. (3) Tumor size: 1 = microscopic focus or foci; 2 = non-microscopic but <= 2 mm.
  4. (4) 9678 cases 0 node examined, 4500 cases with >= 1 node examined.
  5. (5) Log ((number of positive nodes +0.5)/(number of negative nodes + 0.5)). More negative values indicate lower risk of nodal involvement [14].
  6. (6) SEER modified stage grouping: Nx cases (unknown nodal status) are grouped according to the T-stage.