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Table 3 Characteristics of lung cancer cases and control patients in a Spanish population

From: Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain

Variable Cases (n = 516) n (%) Controls (n = 533) n (%) P a
Gender    
   Male 456 (88.4) 460 (86.3)  
   Female 60 (11.6) 73 (13.7) 0.314
Age (yrs), mean (SD) 64.79 (10.99) 63.54 (11.33) 0.090
Smoking Status    
   Never 1 (0.2) 4 (0.7)  
   ETS exposed 35 (6.8) 141 (26.45)  
   Ever 480 (93.0) 388 (73.0) < 0.001
Former 222 (46.8) 224 (60.1)  
Current 252 (53.2) 149 (39.9) < 0.001
Type of tobacco    
   Only black 359 (75.3) 223 (60.6)  
   Only blond 47 (9.8) 84 (22.8)  
   Both 71 (14.9) 61 (16.6) < 0.001
Pack-yearsb, mean (SD) 62.85 (36.18) 40.41 (38.95) < 0.001
Family history of cancer    
   No 272 (57.3) 317 (62.2)  
   Lung cancer 57 (12.0) 35 (6.9)  
   Other cancer 146 (30.7) 158 (31.0) 0.019
Histological type    
   Squamous cell carcinoma 208 (40.3)   
   Adenocarcinoma 152 (29.5)   
   Small cell carcinoma 83 (16.1)   
   Large cell carcinoma 16 (3.1)   
   Non-differentiated 39 (7.6)   
   Others 7 (1.3)   
   Clinical diagnosis 2 (0.4)   
   Missing 9 (1.7)   
  1. a Two-sided χ2 test and Mann-Whitney where appropriate
  2. b Pack-years for ever smokers