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Table 3 Characteristics of lung cancer cases and control patients in a Spanish population

From: Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain

Variable

Cases (n = 516) n (%)

Controls (n = 533) n (%)

P a

Gender

   

   Male

456 (88.4)

460 (86.3)

 

   Female

60 (11.6)

73 (13.7)

0.314

Age (yrs), mean (SD)

64.79 (10.99)

63.54 (11.33)

0.090

Smoking Status

   

   Never

1 (0.2)

4 (0.7)

 

   ETS exposed

35 (6.8)

141 (26.45)

 

   Ever

480 (93.0)

388 (73.0)

< 0.001

Former

222 (46.8)

224 (60.1)

 

Current

252 (53.2)

149 (39.9)

< 0.001

Type of tobacco

   

   Only black

359 (75.3)

223 (60.6)

 

   Only blond

47 (9.8)

84 (22.8)

 

   Both

71 (14.9)

61 (16.6)

< 0.001

Pack-yearsb, mean (SD)

62.85 (36.18)

40.41 (38.95)

< 0.001

Family history of cancer

   

   No

272 (57.3)

317 (62.2)

 

   Lung cancer

57 (12.0)

35 (6.9)

 

   Other cancer

146 (30.7)

158 (31.0)

0.019

Histological type

   

   Squamous cell carcinoma

208 (40.3)

  

   Adenocarcinoma

152 (29.5)

  

   Small cell carcinoma

83 (16.1)

  

   Large cell carcinoma

16 (3.1)

  

   Non-differentiated

39 (7.6)

  

   Others

7 (1.3)

  

   Clinical diagnosis

2 (0.4)

  

   Missing

9 (1.7)

  
  1. a Two-sided χ2 test and Mann-Whitney where appropriate
  2. b Pack-years for ever smokers