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Table 1 Details of RFLPs studied and fragments sizes

From: Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain

Repair

Gene

exon/intron

Enzyme

Polymorphism*

 

Genotype

Fragment sizes (bp)

NER

XPC

intron 9

-

insertion 83 pb

-

PAT -/-

PAT +/+

266

344

 

XPD

exon 10

StyI

G23591A

(rs 1799793)

Asp312Asn

Asp/Asp

Asn/Asn

244+507

33+244+474

 

XPD

exon 23

PstI

A35931C

(rs 13181)

Lys751Gln

Lys/Lys

Gln/Gln

146+290

63+146+227

BER

XRCC1

exon 10

MspI

G28152A

(rs 25487)

Arg399Gln

Arg/Arg

Gln/Gln

132+278+461

278+593

DSBR

XRCC3

exon 7

NcoI

C18067T

(rs 861539)

Thr241Met

Thr/Thr

Met/Met

136

39+97

  1. * Reference SNP accession numbers are indicated for each polymorphism