Table 2 Cox regression analysis for various potential prognostic factors in survival
From: Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis
Overall survival (103 patients) | Disease-free survival (68 patients) in M0 at Nephrectomy | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Unfavorable/favorable characteristics | No. of Patients | Analysis | Relative risk | 95% confidential interval | P value | No. of Patients | Analysis | Relative risk | 95% confidential interval | P value |
Univariate (U) | 11.927 | 4.084 – 34.864 | < 0.0001 | U | 6.357 | 2.109 – 19.163 | 0.001 | ||||
Grade | 01/02/2003 | 32/57/14 | 17/39/12 | ||||||||
Multivariate (M) | 8.658 | 1.647 – 45.529 | 0.0108 | M | 1.006 | 0.175 – 5.776 | 0.9942 | ||||
U | 8.305 | 3.430 – 32.714 | < 0.0001 | U | 4.691 | 2.501 – 13.822 | 0.002 | ||||
pT | > 3/2 < | 31/72 | 13/55 | ||||||||
M | 2.171 | 1.626 – 7.189 | 0.0225 | M | 2.447 | 1.004 – 5.965 | 0.0489 | ||||
U | 9.486 | 3.479 – 25.864 | < 0.0001 | ||||||||
Cell type | sarcomatoid/ | 12/91 | 0/68 | ||||||||
acinar | M | 2.773 | 1.302 – 9.587 | 0.017 | |||||||
U | 11.798 | 3.922 – 35.492 | < 0.0001 | ||||||||
Metastasis | (+)/(-) | 35/68 | 0/68 | ||||||||
M | 4.362 | 1.973 – 19.567 | 0.026 | ||||||||
U | 4.267 | 1.515 – 12.021 | 0.006 | U | 2.028 | 0.592 – 6.952 | 0.2605 | ||||
IFNAR1 | high/low | 47/56 | 25/43 | ||||||||
M | 1.958 | 0.661 – 5.804 | 0.2252 | M | 3.244 | 0.788 – 13.356 | 0.1031 | ||||
U | 10.695 | 4.345 – 26.323 | < 0.0001 | U | 11.03 | 2.920 – 41.655 | 0.0004 | ||||
IFNAR2 | high/low | 35/68 | 18/50 | ||||||||
M | 3.813 | 1.295 – 11.226 | 0.0151 | M | 7.604 | 1.559 – 37.101 | 0.0121 | ||||