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Table 1 Clinicopathologic data of the patients

From: Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis

Grade

pT

Metastasis and Sarcomatoid component

IFNa treatment

Effect of treatment

  

M0 (10 acinar)

IFNa (-) (10 pts)

NED : 10 pts

 

pT1/2 (12 pts)

   

Grade 1 (No. of 14 patients)

 

M1 (lung meta of 2 acinar)

IFNa (+) (2 pts)

CR/PR : 1 pt, PD : 1 pt

 

pT3/4 (2 pts)

M0 (2 acinar)

IFNa (+) (2 pts)

NED : 2 pts

   

IFNa (-) (35 pts)

NED : 32 pts, Meta : 3 pts

  

M0 (39 acinar)

  
 

pT1/2 (45 pts)

 

IFNa (+) (4 pts)

NED : 3 pts, Meta : 1 pt

Grade 2 (No. of 57 patients)

 

M1 (lung meta of 6 acinar)

IFNa (+) (6 pts)

CR/PR : 2 pts, PD : 4 pts

   

IFNa (-) (2 pts)

NED : 1 pt, Meta : 1 pt

  

M0 (7 acinar)

  
 

pT3/4 (12 pts)

 

IFNa (+) (5 pts)

NED : 4 pts, Meta : 1 pt

  

M1 (lung meta of 5 acinar)

IFNa (+) (5 pts)

CR/PR : 2 pts, PD : 3 pts

  

M0 (5 acinar)

IFNa (+) (5 pts)

NED : 2 pts, Meta : 3 pts

 

pT1/2 (15 pts)

   
  

M1 (lung meta of 5 acinar

IFNa (+) (5 pts)

CR/PR : 2 pts, PD : 3 pts

Grade 3 (No. of 32 patients)

 

other organs meta in addition to lung of 5 sarcomatoid)

other systemic therapies including IFNa

PD : 5 pts

  

M0 (5 acinar)

IFNa (+) (5 pts)

NED : 3 pts, Meta : 2 pts

 

pT3/4 (17 pts)

   
  

M1 (lung meta of 5 acinar

IFNa (+) (5 pts)

PD : 5 pts

  

other organs meta in addition to lung of 7 sarcomatoid)

other systemic therapies including IFNa

PD : 7 pts