Figure 5
From: Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
STAT3 decoy ODN decreased the expression of bcl-xl and cyclin D1 in xenografts by Immunohistochemical analysis. The harvested xenografts which treated with decoy or scramble ODN were sectioned and performed immunohistochemical analysis of bcl-xl (A) and cyclin D1 (B) as described in materials and methods. The brown showed the expression levels of bcl-xl and cycln D1; the blue showed the nuclei (original magnification ×400). Each histogram presented the number of bcl-xl and cyclin D1 positive cells per High Power Field in tumor tissues. Statistical significance was determined as # p < 0.05.