Figure 5
From: Functional overload attenuates plantaris atrophy in tumor-bearing rats
Functional overload normalizes myosin heavy chain isoform profiles in TB rats. Plantaris muscles from TB rats had decreased relative percentages of slow, MHC type I isoform which is suggestive of a faster MHC isoform profile. Similar to healthy rats, six weeks after functional overload surgeries were performed plantaris muscle from TB rats had increased relative percentages of slow, MHC type I isoform and decreased relative percentages of fast, MHC type IIb isoform. In fact, the MHC isoform profiles were similar in plantaris muscles from control or TB rats following FO surgeries. N = 6/group. *, Significantly different from sham-operated control rats (p ≤ 0.05). #, Significantly different from sham-operated TB rats (p ≤ 0.05). FO, functional overload; TB, tumor-bearing.