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Table 1 Patient characteristic. Treatment and clinical outcome data for all patients with approved MR spectra.

From: Metabolic profiling of human brain metastases using in vivo proton MR spectroscopy at 3T

Patient no. Sex, Age Primary cancer Brain mets Mets other sites than brain KPS RPA Survival (months) Treatment Time: diagnosis- 1.MRS (weeks) Spectral data TE, VOI1,2
1 F, 52 Breast Single Brain only 90 1 13+ S + 3Gyx10 5 32,1441
2 M, 44 Lung Single Brain only* 90 1 10+ S 1 33,1442
3 a F, 47 Lung Multiple Brain only 90 1 7+ C 0 32,1441
4 a F, 45 Breast Multiple Mediastinum 100 2 15+ S + 3Gyx10 1 33,1442
5 a F, 48 Breast Multiple Skeleton* 100 2 5+ 3Gyx10 0 332
6 F, 57 Lung Multiple Intestinal, jejunum 100 2 7 3Gyx10 4 32,1441
7 M, 63 Lung Multiple Lung, skeleton 100 2 6 3Gyx10 2 32,1441
8 M, 62 Lung Single Skeleton 90 2 4.5 S + 3Gyx10 4 33,1442
9 M, 70 Mal. mel. Multiple Lung, subcutan* 90 2 2 S + 3Gyx10 3 33 in 2 VOI2
10 F, 36 Breast Multiple Liver, skeleton 80 2 9 4Gyx5 (GK) 1 32,1441
11 F, 47 Breast Multiple Liver 80 2 10 3Gyx10 2 32,1441
12 b F, 66 Breast Multiple Brain only 80 2 2 3Gyx10 3 33 in 2 VOI2
13 M, 70 Colon Single Liver, lung 80 2 6 S + 4Gyx5 17 33,1441
14 b F, 80 Lung Multiple Brain only 80 2 0.75 4Gyx5 1 33 in 2 VOI2
15 a F, 71 Lung Multiple Brain only 80 2 3 3Gyx10 4 33 in 2 VOI2
16 F, 72 Breast Multiple Liver, skeleton 60 3 0.5 4Gyx5 2 33,1442
17 M, 69 Colon Single Liver, lung 60 3 6 S + 3Gyx10 5 32,1441
18 a F, 53 Lung Multiple Brain only* 60 3 11+ 4Gyx5 2 33 in 2 VOI2
19 M, 56 Mal. mel. Multiple Epigastrium 60 3 1 No Treatment 2 332 and 321
20 F, 63 Breast Single Lung, skeleton, lymph node 50 3 0.5 No treatment 0 33,1442
21 F, 71 Mal. mel. Single Lung, liver 50 3 1.5 3Gyx10 8 32,1441
  1. F = female, M = male, mets = metastases, a: three MRS follow-up examinations, b: two follow-up MRS examinations, *: brain metastases detected before primary cancer, KPS = Karnofsky Performance Score, RPA = Recursive Partitioning Analysis classification, TE = echo time, VOI1,2 = volume of interest, 1: voxel size: 15 × 15 × 15 mm3, 2: 10 × 10 × 10 mm3. Mal. mel. = malignant melanoma, GK = gamma knife, S = Brain surgery and histopathologic verification, C = Chemotherapy.