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Table 2 Correlation among APN/CD13 expression, migratory potential, and MMP-2 activity in OVCA cell lines

From: Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

  APN/CD13aexpression Migratorybcell counts MMP-2cactivity Doubling time (h) Morphology
ES-2 987.3 168 ± 22 34.2 ± 4.8 18.6 ± 3.7 Fibroblastic
HEY 692.6 153 ± 19 31.5 ± 5.1 22.3 ± 2.4 Fibroblastic
SKOV-3 65.2 125 ± 23 23.9 ± 3.9 18.6 ± 4.7 Fibroblastic
HRA 4.5 129 ± 7 1.9 ± 0.9 17.4 ± 2.6 Fibroblastic
TAOV 7.4 22 ± 8 3.2 ± 2.1 20.2 ± 3.2 Epithelioid
NOS2 5.0 11 ± 4 1.6 ± 1.2 18.9 ± 3.7 Epithelioid
NOS4 3.8 17 ± 6 1.7 ± 0.9 19.4 ± 3.1 Epithelioid
  1. a Mean fluorescence intensity by FACS analysis
  2. b By Transwell migration assay × 200 HPF
  3. c By ELISA assay in conditioned medium (ng/ml)