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Table 2 Correlation among APN/CD13 expression, migratory potential, and MMP-2 activity in OVCA cell lines

From: Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

 

APN/CD13aexpression

Migratorybcell counts

MMP-2cactivity

Doubling time (h)

Morphology

ES-2

987.3

168 ± 22

34.2 ± 4.8

18.6 ± 3.7

Fibroblastic

HEY

692.6

153 ± 19

31.5 ± 5.1

22.3 ± 2.4

Fibroblastic

SKOV-3

65.2

125 ± 23

23.9 ± 3.9

18.6 ± 4.7

Fibroblastic

HRA

4.5

129 ± 7

1.9 ± 0.9

17.4 ± 2.6

Fibroblastic

TAOV

7.4

22 ± 8

3.2 ± 2.1

20.2 ± 3.2

Epithelioid

NOS2

5.0

11 ± 4

1.6 ± 1.2

18.9 ± 3.7

Epithelioid

NOS4

3.8

17 ± 6

1.7 ± 0.9

19.4 ± 3.1

Epithelioid

  1. a Mean fluorescence intensity by FACS analysis
  2. b By Transwell migration assay × 200 HPF
  3. c By ELISA assay in conditioned medium (ng/ml)