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Table 1 Correlation of NIS expression and localization with Akt activation and localization

From: PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer

Tumor classification nuclear pAkt any pAkt any pAkt +loss of PTEN
  n % n % n %
NIS-negative tumors 2/7 28 2/7 28* 0/7 0
NIS-positive tumors 16/26 62 19/26 73* 4/25 16
   NIS intracellular (only) 12/19 63 14/19 74 4/18 22
   NIS plasma membrane (any) 4/7 57 5/7 71 0/7 0
  1. * p < .05