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Table 1 Pathways affected by ST-3 over-expression in MDA-MB-231*

From: Stromelysin-3 over-expression enhances tumourigenesis in MCF-7 and MDA-MB-231 breast cancer cell lines: involvement of the IGF-1 signalling pathway

pathway name accession gene name fold change pathway name accession gene name fold change
MAPK signalling pathway    Wnt signalling pathway   
  NM_004630 MAP4K2 3.7   NM_005044 PRKX -2.1
  NM_016151 thousand and one amino acid protein kinase 2.6   NM_004423 DVL3 2.5
  NM_002524 NRAS 2.3   NM_002335 LRP5 -2.0
  AF188611 HSPA5 -2.1   NM_003507 FZD7 2.4
  NM_005044 PRKX -2.1   BC002646 JUN -2.2
  M54968 KRAS2 -2.1   NM_002760 PRKY 3.0
  NM_006609 MAP3K2 -2.0   BC011655 CTBP1 7.3
  NM_006256 PKN2 5.3   NM_002731 PRKACB 2.7
  BC002646 JUN -2.2 Ribosome    
  NM_007181 MAP4K1 3.4   BF570115 RPLP0 2.7
  NM_001791 CDC42 5.7   AK093246 RPL13 2.5
  NM_000719 CACNA1C 2.8   BC022357 RPL17 2.0
  AL050044 GADD45B 2.3   NM_001022 RPS19 5.5
  BC003623 YWHAZ 6.7   NM_016093 RPL26L1 2.3
  AK124299 PPM1A 2.1   NM_001017 RPS13 9.1
  AF233453 PRKCBP1 2.4 Apoptosis    
  NM_003010 MAP2K4 2.6   NM_003844 TNFRSF10A -2.2
  NM_002760 PRKY 3.0   NM_006218 PIK3CA 2.0
  NM_002731 PRKACB 2.7   NM_000633 BCL2 2.4
  NM_002609 PDGFRB 3.3   U84408 MYD88 3.2
Cell cycle      NM_002731 PRKACB 2.7
  BC039904 HDAC4 3.0 Jak-STAT signalling pathway   
  BC008026   2.9   NM_001560 IL13RA1 2.9
  NM_005915 MCM6 2.1   NM_006218 PIK3CA 2.0
  NM_004725 BUB3 3.6   BC030949 PTPN11 2.6
  NM_000075 CDK4 2.4   NM_000418 IL4R 2.5
  NM_004219 PTTG1 3.4   BC028068 JAK3 -2.2
  NM_031966 CCNB1 2.0 Ubiquitin mediated proteolysis   
  NM_001786 CDC2 2.8   NM_003334 UBE1 -2.1
  AL050044 GADD45B 2.3   NM_181838 UBE2D2 3.1
  NM_004064 CDKN1B 2.4   AB012109 ANAPC10 2.4
  NM_006607 PTTG2 2.6   NM_033632 FBXW7 2.7
  BC027989 CDK6 2.6 Integrin-mediated cell adhesion   
* analysed by BioRag     NM_005167 RHOC 2.4
      NM_001791 CDC42 5.7
      NM_016848 SHC3 2.2