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Table 3 CYP3A4 and CYP3A5 genotypes in colorectal cancer patients according tumor site.

From: Genetic variability in CYP3A4 and CYP3A5in primary liver, gastric and colorectal cancer patients

CYP3A4 CYP3A5 NON-SIGMOID
N (FREQUENCY; 95% C.I.)
SIGMOID
N (FREQUENCY; 95% C.I.)
RECTUM
N (FREQUENCY; 95% C.I.)
*1A/*1A *3/*3 33 (73.3; 60.4–86.3) 40 (78.4; 67.1–89.7) 48 (87.3; 78.5–96.1)
*1A/*1A *1/*3 6 (13.3; 3.4–23.3) 6 (11.8; 2.9–20.6) 6 (10.9; 2.7–19.1)
*1A/*1B *3/*3 4 (8.8; 0.6–17.2)* 1 (2.0; 0–5.8) 0
*1A/*1B *1/*3 2 (4.4; 0–10.5) 3 (5.9; 0–12.3) 1 (1.8; 0–5.3)
*1B/*1B *1/*3 0 1 (2.0; 0–5.8) 0
  1. *p < 0.0015 compared to healthy subjects