From: Genetic variability in CYP3A4 and CYP3A5in primary liver, gastric and colorectal cancer patients
CYP3A4 | CYP3A5 | Liver cancer N (Frequency; 95% C.I.) | Stomach cancer N (Frequency; 95% C.I.) | Colorectal cancer N (Frequency; 95% C.I.) | Control subjects N (Frequency; 95% C.I.) |
---|---|---|---|---|---|
*1A/*1A | *3/*3 | 144 (80.9; 75.1–86.7) | 74 (90.2; 83.8–96.7) | 121 (80.1; 73.8–86.5) | 134 (82.2; 76.4–88.1) |
*1A/*1A | *1/*3 | 17 (9.6; 5.2–13.9) | 2 (2.4; 0–5.8) | 18 (11.9; 6.8–17.1) | 14 (8.6; 4.3–12.9) |
*1A/*1A | *1/*1 | 0 | 0 | 0 | 1 (0.6; 0–1.8) |
*1A/*1B | *3/*3 | 5 (2.8; 0.4–5.2) | 1 (1.2; 0–3.6) | 5 (3.3; 0.5–6.2) | 1 (0.6; 0–1.8) |
*1A/*1B | *1/*3 | 12 (6.7; 3.1–10.4) | 5 (6.1; 0.9–11.3) | 6 (4.0; 0.9–7.1) | 12 (7.4; 3.3–11.4) |
*1A/*1B | *1/*1 | 0 | 0 | 0 | 1 (0.6; 0–1.8) |
*1B/*1B | *1/*3 | 0 | 0 | 1 (0.7; 0–2.0) | 0 |