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Figure 1 | BMC Cancer

Figure 1

From: Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

Figure 1

Stat3 phosphorylation is elevated in rhabdomyosarcoma, osteosarcoma and other soft-tissue sarcoma tissues and cell lines. (A) Immunohistochemical staining in sarcoma tissues: a. normal skeletal muscle tissue, b. alveolar rhabdomyosarcoma, c. normal osteo tissue, d. osteosarcoma. The nuclei were counterstained with hematoxylin blue. Image magnifications are 100×. Images of higher magnification (400×) are shown in the insets of b and c. The arrow indicates a cell with nuclear and cytoplasmic p-Stat3 staining. Western blots also show elevated p-Stat3 in (B) osteosarcoma and leiomyosarcoma cell lines and (C) rhabdomyosarcoma cell lines.

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BMC Cancer

ISSN: 1471-2407

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