Figure 4From: Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomasScore plot of first principal component (PC1) versus second principal component (PC2) from partial least square (PLS) regression analysis of tumor cell fraction to spin-echo spectral data (A), the corresponding loading profile of PC1 (B), and the predicted versus measured tumor cell fraction (C). In (A) and (C) each point represents the data of a single biopsy. In (A) the color code for tumor cell fractions (%) is shown. Spectral assignments are abbreviated in (B): β-Glc, β-glucose; Lac, lactate; m-Ino, myo-inositol; Cre, creatine; Tau, taurine; GPC, glycerophosphocholine; PC, phosphocholine; Cho, choline. The Pearson correlation coefficient and p-value are marked in (C). Total residual y-variance and root mean square error of prediction were minimised by retaining 2 PCs in the model. These two PCs accounted for 45% of the total x-variation, and 66% of the total y-variation.Back to article page