Figure 8

Loss of TRAIL expression pattern in oral leukoplakia with severe dysplasia. A: Hematoxylin and eosin staining (× 100); B: Immunohistochemical staining for TRAIL (× 100). Note that TRAIL expression is mostly lost in dysplastic epithelium (arrow). In contrast, mononuclear immune cell infiltrate (MNC) associated with dysplasia reveals intense staining for TRAIL.