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Table 2 Rare allele carriage rates in breast cancer and controls

From: Endostatin gene variation and protein levels in breast cancer susceptibility and severity

Groups

Rare allele (A) carriage rate (%)

Odds Ratio (95% CI)

Test statistic (p value)#

 

Cancer

Controls

  

Overall

136/846 (16.1%)

115/707 (16.3%)

0.99 (0.75–1.29)

×2 = 0.001; p = 0.97

Positive family history*

38/231 (16.5%)

22/153 (14.4%)

0.17 (0.66–2.07)

×2 = 0.16; p = 0.69

Negative family history*

98/615 (15.9%)

93/554 (16.8%)

0.94 (0.69–1.28)

×2 = 0.1; p = 0.75

Young patients** vs. controls

20/130 (15.4%)

115/707 (16.3%)

0.94 (0.56–1.57)

×2 = 0.01; p = 0.90

  1. # Pearson's chi-square test (with Yates correction where applicable)
  2. *Family history: either first or second-degree relative with breast cancer
  3. **Young cancer patients: </= 50 years of age