Table 4 Gene expression of MSSM cells in relation to HMEC cells Down regulated Genes in MSSM cells.
From: Transcription profiles of non-immortalized breast cancer cell lines
| Â | SAM | t-test | Atlas | Â | Â | ||
|---|---|---|---|---|---|---|---|
Name | Score(d) | Fold | p value | Ratio | Diff | Protein/gene | Gene ontology |
SFN | -18.5106 | -134.41 | 2.71E-08 | -76.89 | -14875 | 14-3-3 protein sigma; stratifin | cell communication cellular physiological process metabolism |
SPINT2 | -14.6598 | -37.30 | 4.10E-07 | -39.72 | -5653 | bikunin; hepatocyte growth factor activator inhibitor 2 | cellular physiological process |
LAMB2 | -11.3177 | -12.53 | 8.94E-06 | -12.09 | -5510 | laminin beta 2 subunit precursor | cell communication |
ITGA7 | -11.0881 | -13.03 | 3.24E-05 | -12.06 | -12577 | integrin alpha 7B precursor | cell communication cellular physiological process morphogenesis |
CDH3 | -8.9105 | -12.11 | 3.62E-05 | -15.23 | -4283 | cadherin 3; P-cadherin | cell communication response to stimulus |
PLAU | -7.9173 | -10.37 | 2.18E-05 | -22.29 | -2512 | urokinase-type plasminogen activator | cell communication cellular physiological process metabolism response to stimulus |
ITGB4 | -7.9148 | -22.09 | 2.86E-05 | -20.11 | -16722 | integrin beta 4; CD104 antigen | cell communication |
TPBG | -7.6578 | -5.42 | 2.34E-04 | -4.84 | -1922 | 5T4 oncofetal antigen precursor | cell communication cellular physiological process |
RPS6KA1 | -7.5622 | -3.37 | 5.64E-08 | -3.21 | -3450 | ribosomal protein S6 kinase alpha1 | cell communication metabolism |
EDG4 | -7.2225 | -4.69 | 6.71E-04 | -4.45 | -1208 | G protein-coupled receptor | cell communication |
IRF6 | -6.7854 | -120.19 | 4.26E-11 | 137.08 | -1905 | interferon regulatory factor 6 | metabolism |
LITAF | -6.7240 | -3.73 | 1.49E-03 | -3.53 | -2311 | PIG7 | cell communication metabolism regulation of cellular process |
SEMA3F | -6.4547 | -3.55 | 1.90E-04 | -2.68 | -1510 | semaphorin | Gen with GO but NOT at level 3 biological process |
NOTCH1 | -6.0498 | -2.95 | 7.96E-04 | -2.86 | -1883 | neurogenic locus notch protein homolog 1 | metabolism response to stimulus |
ITGA6 | -5.9332 | 1052.63 | 6.90E-07 | Down | -1273 | integrin alpha 6 precursor | cell communication cellular physiological process |
DSP | -5.9015 | 1190.48 | 8.57E-07 | Down | -1463 | desmoplakin I & II | morphogenesis |
CDA | -5.4364 | -21.03 | 4.64E-07 | -18.79 | -3523 | cytidine deaminase | metabolism |
JUP | -5.3936 | -6.77 | 9.66E-07 | -6.47 | -6165 | junction plakoglobin; desmoplakin III | cell communication |
JAG2 | -5.2949 | -4.22 | 1.20E-03 | -4.30 | -1841 | jagged2 | cell communication cellular physiological process morphogenesis regulation of cellular process response to stimulus |
SERPINB1 | -4.8852 | -6.11 | 1.38E-04 | -5.46 | -1960 | leukocyte elastase inhibitor | Gen with GO but NOT at level 3 biological process |
BTG2 | -4.8636 | -24.34 | 3.84E-05 | -11.74 | -752 | btg protein precursor; NGF- inducible anti-proliferative protein PC3 | cellular physiological process metabolism regulation of cellular process response to stimulus |