Table 2 TP53 mutations in breast tumors
From: Breast tumor copy number aberration phenotypes and genomic instability
Tumor Sample | CGH Subtype | TP53Mutation | Copy Number | Loss of Function1 | Gain of Function1 | Dom. Neg.1 | TS1 |
|---|---|---|---|---|---|---|---|
S0013 | Complex | Y205D | Loss | NA | NA | NA | NA |
S0184 | Complex | R175H | Loss | Yes | Yes | Yes | No |
S0269 | Complex | M237I | Loss | NA | NA | No | NA |
S1511 | Complex | C275Y | Loss | NA | NA | No | NA |
S0001 | Mixed amplifier | Y234C | No Loss | Yes | NA | NA | Yes |
S0043 | Mixed amplifier | Y163C | No Loss | Yes | Yes | No | NA |
S0055 | Mixed amplifier | 196 Stop | Loss | NA | NA | No | NA |
S0126 | Mixed amplifier | intron 5/6 | Loss | NA | NA | NA | NA |
S1503 | Mixed amplifier | C176Y | Loss | Yes | NA | Yes | NA |
S1579 | Mixed amplifier | G245C | Loss | Yes | NA | Yes | NA |