Figure 1From: Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer Novel somatic mtDNA mutations in esophageal cancer detected by TTGE and sequencing. A: Homoplasmic to heteroplasmic G10500A (A11T in ND4L) mutation in case E12 B: Heteroplasmic change of A1544T in 12S rRNA in case E05 C: Heteroplasmic deletion of 11bp (del TAACAACCCCC)at np10941 (110 × in ND4) in case E18 D: Heteroplasmic to homoplasmic change of A9182G (N219S) in ATPase 6 in case E15. The multiple banding pattern of TTGE in tumor confirms heteroplasmic change. tu: tumor, nl: normalBack to article page